High-Purity D-Proline Chiral Amino Acid for Peptide Synthesis from China Suppliers and Factory - CAS 344-25-2
| Product Category | Amino Acid Pharmaceutical Intermediate |
| Appearance | White to off-white powder |
| Melting Point | 223℃ |
| Solubility | Methanol (Slightly), Water (Sparingly) |
| Optical Rotation | [α]22/D +85.0°, c = 4 in H₂O |
| Water Solubility | soluble >1000 g/L (20 ℃) |
| Density | 1.19 |
| Boiling Point | 252.2 ℃ at 760 mmHg |
| Refractive Index | 85° (C=4, H₂O) |
| Flash Point | 106.3 ℃ |
| Vapour Pressure | 0.0±1.1 mmHg at 25℃ |
| pKa | 1.952 (at 25℃) |
D-Proline is a high-purity, non-proteinogenic amino acid that serves as a vital chiral building block in modern chemical synthesis. As the optical isomer of the naturally occurring L-Proline, this white to off-white crystalline powder is indispensable for the creation of chiral ligands, catalysts, and specialized pharmaceuticals. Its unique secondary amine structure allows it to provide precise stereochemical control in asymmetric synthesis, making it a favorite among research chemists and drug developers.
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High Optical PurityGuaranteed high enantiomeric excess (typically ee over 99%), ensuring maximum precision and selectivity in asymmetric catalytic reactions.
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Versatile Chiral Building BlockActs as a fundamental intermediate for synthesizing D-type peptides, chiral drugs, and advanced organic molecules.
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Excellent SolubilityHighly soluble in water and slightly soluble in ethanol, allowing for flexible processing in various aqueous or organic solvent systems.
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Stable Crystalline FormProvided as a stable crystalline powder with a melting point of approximately 215 to 223 degrees Celsius (with decomposition), facilitating easy storage and handling.
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Organocatalysis EssentialWidely utilized in the synthesis of chiral catalysts, such as those used in the Hajos-Parrish-Eder-Sauer-Wiechert reaction.
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Pharmaceutical Grade QualityManufactured under strict quality control to ensure low heavy metal content and minimal impurities, suitable for pharmaceutical research.
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Natural Isomer AlternativeProvides the necessary structural "mirror image" for researchers investigating the biological effects of D-amino acids in protein engineering.
Sample packaging: 1g/5g/10g in glass bottles (with inner sealing);
Bulk packaging: 25kg in cardboard drums (inner packaging with vacuum aluminum foil bags).
Neutral packaging or customer-specified brand packaging is supported; prior communication and confirmation are required.
Store in a cool and dark environment (temperature < 15°C), sealed under an inert gas atmosphere. Avoid contact with oxidizing agents and prevent moisture absorption.
18 months shelf life when stored in original packaging (sealed condition).
Annual production capacity of 50 tons. Popular products are usually in stock (in-stock orders shipped within 72 hours); customized orders delivered within 7–15 working days.
Samples: DHL/UPS international express (3–7 days);
Bulk cargo: Sea/air freight via logistics partners (e.g., Maersk). Full customs declaration documents provided.
Sample orders: 100% prepayment;
Bulk orders: T/T (30% deposit, 70% against copy of B/L). L/C payment terms are negotiable.
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Q1Is the product's chiral purity stable for large-scale production?A1The chiral purity remains ≥99% in mass production, and we provide chiral detection reports for each batch.
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Q2Can samples be provided before bulk procurement?A2Free 1g samples are available; customers only need to bear the shipping cost.
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Q3What is the minimum order quantity (MOQ) for bulk orders of D-Proline?A3The minimum order quantity for bulk procurement is typically 1 kg. Please contact our sales team for specific requirements and competitive pricing.
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Q4What certifications and quality documents are available for D-Proline?A4We provide a Certificate of Analysis (CoA), HPLC chiral purity report, MSDS/SDS, and other relevant quality documentation upon request for each batch.
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Q5Can D-Proline be used directly in pharmaceutical manufacturing?A5Our D-Proline is manufactured under strict quality control to meet pharmaceutical research-grade standards. For direct use in GMP-regulated drug manufacturing, please consult our technical team for compliance documentation.
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Q6Are custom packaging and private label options available?A6Yes, we support both neutral packaging and customer-specified brand (private label) packaging. Prior communication and order confirmation are required before production.