L-Proline
Physical & Chemical Properties
| Product Category | Amino Acid Pharmaceutical Intermediate | ||||||
| Appearance | White crystalline powder | ||||||
| Melting Point | 228℃(dec.)(lit.) | ||||||
| Solubility | H2O: 50 mg/mL | ||||||
| Optical Rotation | [α]20/D 85.0±1.0°, c = 5% in H2O | ||||||
| Water Solubility | soluble | ||||||
| Density | 1.35 | ||||||
| Boiling point | 215.41℃ (rough estimate) | ||||||
| Refractive index | -85°(C=4, H2O) | ||||||
| Flash Point | 106.3 ℃ | ||||||
| Vapour Pressure | 0.0±1.1 mmHg at 25℃ | ||||||
| pKa | 1.95, 10.64(at 25℃) | ||||||
Product Description
L-Proline is a high-purity, proteinogenic amino acid essential for the synthesis of collagen, the primary structural protein in skin, joints, and connective tissues. This white crystalline powder features a unique cyclic secondary amine structure, providing exceptional conformational rigidity to peptide chains. Widely used in the pharmaceutical, food, and cosmetic industries, L-Proline acts as a critical building block for anti-aging skin care, joint health supplements, and chiral catalysts in organic synthesis. Its high solubility and stability make it an ideal choice for manufacturers seeking consistent, high-performance ingredients for nutritional and medical formulations.
Product Features
Collagen Precursor: Vital for skin elasticity, wound healing, and maintaining healthy joints and tendons.
High Optical Purity: Enantiomeric purity typically ≥99%, ensuring precise results in chiral drug synthesis and research.
Versatile Applications: Extensively used as a nutritional additive, pharmaceutical intermediate, and stabilizer in cosmetics.
Superior Solubility: Easily dissolves in water (approx. 162g/100mL at 25°C), facilitating effortless formulation and processing.
Stable & Reliable: Features high thermal stability with a melting point of 220-222°C, ideal for industrial storage and handling.
Organic Catalyst: Acts as an efficient organocatalyst for asymmetric reactions like aldol condensations.
Packaging & Specifications
Packaging Specifications
Sample packaging: 1g/5g/10g in glass bottles (with inner sealing);
Bulk packaging: 25kg in cardboard drums (inner packaging with vacuum aluminum foil bags).
Packaging Customization
Neutral packaging or customer-specified brand packaging is supported; prior communication and confirmation are required.
Storage Conditions
Store in a cool and dark environment (temperature < 15°C), sealed under an inert gas atmosphere. Avoid contact with oxidizing agents and prevent moisture absorption.
Shelf Life
18 months shelf life when stored in original packaging (sealed condition).
Quality Compliance & Assurance
Supply Service & Description
Supply Capacity
Supply capacity: Annual production capacity of 50 tons. Popular products are usually in stock (in-stock orders shipped within 72 hours); customized orders are delivered within 7-15 working days based on process requirements.
Shipping options
Samples: DHL/UPS international express (3-7 days delivery);
Bulk cargo: Cooperate with logistics providers (e.g., Maersk) via sea/air freight. Full set of customs declaration documents are provided to ensure compliant customs clearance.
Payment terms
Sample orders: 100% prepayment;
Bulk orders: T/T (30% deposit, 70% payment against copy of bill of lading). L/C payment terms are negotiable.
Related & Extended Content
Recommended related products
(R)-3-Boc-aminopiperidine (CAS: 309956-78-3), Alogliptin benzoate (CAS: 850649-62-6)
Frequently Asked Questions（FAQ）
Q1: Is the product's chiral purity stable for large - scale production?
A1: The chiral purity remains ≥99% in mass production, and we provide chiral detection reports for each batch.
Q2: Can samples be provided before bulk procurement?
A2: Free 1g samples are available, and customers only need to bear the shipping cost.