L-Pyroglutamic Acid Suppliers in China | Pharmaceutical Grade Factory | C5H7NO3 Intermediate
| Product Category | Amino Acid Pharmaceutical Intermediate |
| Appearance | White fine crystals |
| Melting Point | 152–162 ℃ |
| Solubility | 10–15 g/100 mL (20 ºC) |
| Optical Rotation | [α]20/D 10.5±1°, c = 5% in H₂O |
| Water Solubility | 10–15 g/100 mL (20 ℃) |
| Density | 1.38 |
| Boiling Point | 453.1 ℃ at 760 mmHg |
| Refractive Index | -10° (C=5, H₂O) |
| Flash Point | 227.8 ℃ |
| Vapour Pressure | 0.0±2.0 mmHg at 25 ℃ |
| pKa | 3.32 (at 25 ℃) |
L-Pyroglutamic acid is a naturally occurring amino acid derivative and a key cyclic intermediate in the gamma-glutamyl cycle. This white crystalline powder is highly valued in the pharmaceutical and cosmetic industries for its exceptional moisture-binding properties and its role as a chiral building block. Often utilized as a natural humectant (as PCA), it helps maintain skin hydration and barrier function. Additionally, it serves as a critical starting material for synthesizing bioactive peptides and neuroprotective agents, offering high purity and biological compatibility for advanced health and beauty formulations.
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Natural Humectant A primary component of the skin's Natural Moisturizing Factor (NMF), providing intense hydration in skincare products.
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Chiral Intermediate Acts as an essential starting material for the synthesis of complex chiral drugs and peptidomimetics.
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High Purity Standards Manufactured with an assay of 99% or higher, ensuring consistent quality for sensitive pharmaceutical applications.
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Excellent Safety Profile Biodegradable and non-irritating, making it ideal for clean-label cosmetic and personal care formulations.
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Superior Solubility Readily soluble in water and alcohol, allowing for easy integration into various liquid and cream-based systems.
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Thermal Stability Maintains structural integrity under standard processing conditions with a melting point of 160 to 163 degrees Celsius.
📦 Packaging Specifications
Sample packaging: 1g / 5g / 10g in glass bottles (with inner sealing);
Bulk packaging: 25 kg in cardboard drums (inner packaging with vacuum aluminum foil bags).
🎨 Packaging Customization
Neutral packaging or customer-specified brand packaging is supported; prior communication and confirmation are required.
❄️ Storage Conditions
Store in a cool and dark environment (temperature < 15°C), sealed under an inert gas atmosphere. Avoid contact with oxidizing agents and prevent moisture absorption.
🗓️ Shelf Life
18 months shelf life when stored in original packaging (sealed condition).
🏭 Supply Capacity
Annual production capacity of 50 tons. Popular products are usually in stock (orders shipped within 72 hours); customized orders delivered within 7–15 working days based on process requirements.
✈️ Shipping Options
Samples: DHL/UPS international express (3–7 days delivery);
Bulk cargo: Cooperate with logistics providers (e.g., Maersk) via sea/air freight. Full customs declaration documents provided for compliant clearance.
💳 Payment Terms
Sample orders: 100% prepayment;
Bulk orders: T/T (30% deposit, 70% payment against copy of bill of lading). L/C payment terms are negotiable.
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Q Is the product's chiral purity stable for large-scale production?
The chiral purity remains ≥99% in mass production, and we provide chiral detection reports for each batch.
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Q Can samples be provided before bulk procurement?
Free 1g samples are available, and customers only need to bear the shipping cost.
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Q What certifications does the product comply with?
L-Pyroglutamic acid is manufactured in compliance with GMP standards and is supported by comprehensive quality documentation including COA, MSDS, and third-party test reports.
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Q Is custom packaging or private labeling available?
Yes. Both neutral packaging and customer-specified brand packaging are supported. Please confirm details prior to placing your order.
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Q What is the minimum order quantity (MOQ) for bulk orders?
The MOQ for bulk orders is typically 25 kg (one drum). Please contact our sales team for specific quantity requirements and pricing.
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Q How should L-Pyroglutamic acid be stored to maintain its quality?
Store in a cool, dark environment at temperatures below 15°C, sealed under an inert gas atmosphere. Keep away from oxidizing agents and moisture to ensure an 18-month shelf life.