L-Pyroglutamic acid
Physical & Chemical Properties
| Product Category | Amino Acid Pharmaceutical Intermediate | ||||||
| Appearance | White fine crystals | ||||||
| Melting Point | 152-162℃ | ||||||
| Solubility: | 10-15 g/100 mL (20 ºC) | ||||||
| Optical Rotation | [α]20/D 10.5±1°, c = 5% in H2O | ||||||
| Water Solubility | 10-15 g/100 mL (20 ℃) | ||||||
| Density | 1.38 | ||||||
| Boiling point | 453.1℃ at 760 mmHg | ||||||
| Refractive index | -10 ° (C=5, H2O) | ||||||
| Flash Point | 227.8℃ | ||||||
| Vapour Pressure | 0.0±2.0 mmHg at 25℃ | ||||||
| pKa | 3.32(at 25℃) | ||||||
Product Description
L-Pyroglutamic acid is a naturally occurring amino acid derivative and a key cyclic intermediate in the gamma-glutamyl cycle. This white crystalline powder is highly valued in the pharmaceutical and cosmetic industries for its exceptional moisture-binding properties and its role as a chiral building block. Often utilized as a natural humectant (as PCA), it helps maintain skin hydration and barrier function. Additionally, it serves as a critical starting material for synthesizing bioactive peptides and neuroprotective agents, offering high purity and biological compatibility for advanced health and beauty formulations.
Product Features
Natural Humectant: A primary component of the skin's Natural Moisturizing Factor (NMF), providing intense hydration in skincare products.
Chiral Intermediate: Acts as an essential starting material for the synthesis of complex chiral drugs and peptidomimetics.
High Purity Standards: Manufactured with an assay of 99% or higher, ensuring consistent quality for sensitive pharmaceutical applications.
Excellent Safety Profile: Biodegradable and non-irritating, making it ideal for clean-label cosmetic and personal care formulations.
Superior Solubility: Readily soluble in water and alcohol, allowing for easy integration into various liquid and cream-based systems.
Thermal Stability: Maintains structural integrity under standard processing conditions with a melting point of 160 to 163 degrees Celsius.
Packaging & Specifications
Packaging Specifications
Sample packaging: 1g/5g/10g in glass bottles (with inner sealing);
Bulk packaging: 25kg in cardboard drums (inner packaging with vacuum aluminum foil bags).
Packaging Customization
Neutral packaging or customer-specified brand packaging is supported; prior communication and confirmation are required.
Storage Conditions
Store in a cool and dark environment (temperature < 15°C), sealed under an inert gas atmosphere. Avoid contact with oxidizing agents and prevent moisture absorption.
Shelf Life
18 months shelf life when stored in original packaging (sealed condition).
Quality Compliance & Assurance
Supply Service & Description
Supply Capacity
Supply capacity: Annual production capacity of 50 tons. Popular products are usually in stock (in-stock orders shipped within 72 hours); customized orders are delivered within 7-15 working days based on process requirements.
Shipping options
Samples: DHL/UPS international express (3-7 days delivery);
Bulk cargo: Cooperate with logistics providers (e.g., Maersk) via sea/air freight. Full set of customs declaration documents are provided to ensure compliant customs clearance.
Payment terms
Sample orders: 100% prepayment;
Bulk orders: T/T (30% deposit, 70% payment against copy of bill of lading). L/C payment terms are negotiable.
Related & Extended Content
Recommended related products
(R)-3-Boc-aminopiperidine (CAS: 309956-78-3), Alogliptin benzoate (CAS: 850649-62-6)
Frequently Asked Questions（FAQ）
Q1: Is the product's chiral purity stable for large - scale production?
A1: The chiral purity remains ≥99% in mass production, and we provide chiral detection reports for each batch.
Q2: Can samples be provided before bulk procurement?
A2: Free 1g samples are available, and customers only need to bear the shipping cost.